This volume shows the deep changes in architecture by the impact of the AI and the climate fast evolution in mankind. We are just now with the Covid to feel these changes, but it is just a start point, neither the medical sciences nor architecture in itself will never be the same. Just to announce that the next volumes in ARQUITECTONICS will analyze how education architecture andpolitics will evaluate altogether, the next years, in a new political, physical and cultural environment. First step:The International Conference in Madrid, in June 2023, by The Piaget International Society about BRINGING THEORY TO THE FOREFRONT OF DEVELOPMENTAL NEUROSCIENCE.