Continuing the (neo-)classical tradition of von Thünen, Launhardt, Weber, Palander, and Lösch this book offers a fresh approach to the location of industries and other economic activities, of market areas, spatial price distribution, locational specialization, urban and transportation systems, and spatial interaction in general. It uses elementary economic reasoning supported by simple mathematical models, some classical, some new. The mathematical methods are presented in numbered Mathematical Notes. The author has been active in this field since 1950.